BioPro 0.1.4

BioPro is a bioinformatics pipeline that predicts the functional targets of RNA-binding protein and the biological processes to which these functional targets contribute.

Predicting Biochemical Pathways Involving Target RBP

BioPro is a bioinformatics pipeline that processes and analyzes eCLIP data of RNA-binding proteins (RBP) to predict the functional targets of RBP and biological processes to which the functional targets of RBP contributes.

BioPro pipeline cleans raw eCLIP data of a target RBP with Cutadapt and aligns the RNA sequence with STAR. Peak calling is then performed with PureCLIP. Then, based on the peaks, PRAS predicts the functional target genes of RBP and produces a ranked gene list. The pipeline then performs gene ontology (GO) analysis on the top 5% ranked genes to predict the biological processes.

Install

Install via source code

To install via source code, clone our github repo and run:

git clone https://github.com/Crazy-Jack/SuperdopeBioinformatics
bash install.sh

Install via pip

Or you can directly install our software from pip:

pip install Team3