Skip to main content

Estimating and removing ambient expression in scRNA-seq data

Project description

CellClear: Enhancing scRNA-seq Data Quality via Biologically-Informed Ambient RNA Correction

Installation

CellClear can be installed from the python repository pypi (https://pypi.org/project/CellClear/)

Running CellClear

A typical CellClear run with default settings would look like this:

CellClear correct_expression --filtered_mtx_path filtered_feature_bc_matrix --raw_mtx_path raw_feature_bc_matrix --prefix test --output .

For full usage details with additional options, see "CellClear correct_expression --help".

CellClear outputs

(1) Determine the ambient RNA expression level

(2) Give the identified ambient genes

(3) Remove the ambient RNA from each cell and output a new matrix

Project details


Download files

Download the file for your platform. If you're not sure which to choose, learn more about installing packages.

Source Distribution

cellclear-0.0.1.tar.gz (4.6 kB view details)

Uploaded Source

Built Distribution

CellClear-0.0.1-py3-none-any.whl (5.6 kB view details)

Uploaded Python 3

File details

Details for the file cellclear-0.0.1.tar.gz.

File metadata

  • Download URL: cellclear-0.0.1.tar.gz
  • Upload date:
  • Size: 4.6 kB
  • Tags: Source
  • Uploaded using Trusted Publishing? No
  • Uploaded via: twine/5.1.1 CPython/3.12.2

File hashes

Hashes for cellclear-0.0.1.tar.gz
Algorithm Hash digest
SHA256 2c1804d2ed7732dfb3240716bd0f64e98dbc6677db80bfcec220940e4e8b2d48
MD5 0249000533ca0b1cd12fc394f618f78b
BLAKE2b-256 c1f89ee72cf5a8a35adc65c2a1d88550ecd1880ca0b7916aaba5e5ada88e6467

See more details on using hashes here.

File details

Details for the file CellClear-0.0.1-py3-none-any.whl.

File metadata

  • Download URL: CellClear-0.0.1-py3-none-any.whl
  • Upload date:
  • Size: 5.6 kB
  • Tags: Python 3
  • Uploaded using Trusted Publishing? No
  • Uploaded via: twine/5.1.1 CPython/3.12.2

File hashes

Hashes for CellClear-0.0.1-py3-none-any.whl
Algorithm Hash digest
SHA256 1cf5d29b066f3de3f482daf1edf5df7140bcd6d3af582a9caa9217e3d78348b5
MD5 ec131e9b369555f9143cb4cab81d0c70
BLAKE2b-256 39d7fa7647d6f097496ebac27ae4db2aac14c459915cbe33d8b3276e64871934

See more details on using hashes here.

Supported by

AWS AWS Cloud computing and Security Sponsor Datadog Datadog Monitoring Fastly Fastly CDN Google Google Download Analytics Microsoft Microsoft PSF Sponsor Pingdom Pingdom Monitoring Sentry Sentry Error logging StatusPage StatusPage Status page