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single cell RNA profiling analysis of imaging-based spatial transcriptomics data

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News (16/07/24)

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If you have any questions relative to the package or bug, please open an issue in this repository.

ComSeg framework

A detail documentation is available at https://comseg.readthedocs.io/

Single cell spatial RNA profiling

ComSeg is an algorithm for single cell spatial RNA profiling in image-based transcriptomic data.

It takes as input a csv with the spot coordinates and output an anndata object with the genes expression and coordinates of each cell.

Citation

Defard, T., Laporte, H., Ayan, M. et al. A point cloud segmentation framework for image-based spatial transcriptomics. Commun Biol 7, 823 (2024). https://doi.org/10.1038/s42003-024-06480-3

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