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LANDMark: An ensemble approach to the supervised selection of biomarkers in high-throughput sequencing data

Project description

LANDMark

CI

Implementation of a decision tree ensemble which splits each node using learned linear and non-linear functions.

Install

From PyPI:

pip install LANDMarkClassifier

From source:

git clone https://github.com/jrudar/LANDMark.git
cd LANDMark
pip install .
# or create a virtual environment
python -m venv venv
source venv/bin/activate
pip install .

Interface

An overview of the API can be found here.

Usage and Examples

Examples of how to use LANDMark can be found here.

Contributing

To contribute to the development of LANDMark please read our contributing guide

References

Rudar, J., Porter, T.M., Wright, M., Golding G.B., Hajibabaei, M. LANDMark: an ensemble 
approach to the supervised selection of biomarkers in high-throughput sequencing data. 
BMC Bioinformatics 23, 110 (2022). https://doi.org/10.1186/s12859-022-04631-z

Pedregosa F, Varoquaux G, Gramfort A, Michel V, Thirion B, Grisel O, et al. Scikit-learn: 
Machine Learning in Python. Journal of Machine Learning Research. 2011;12:2825–30. 

Kuncheva LI, Rodriguez JJ. Classifier ensembles with a random linear oracle. 
IEEE Transactions on Knowledge and Data Engineering. 2007;19(4):500–8. 

Geurts P, Ernst D, Wehenkel L. Extremely Randomized Trees. Machine Learning. 2006;63(1):3–42. 

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