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Parsing, validation, compilation, and data exchange of Biological Expression Language (BEL)

Project description

PyBEL is a pure Python package for parsing and handling biological networks encoded in the Biological Expression Language (BEL). It also facilitates data interchange between common formats and databases such as NetworkX, JSON, CSV, SIF, Cytoscape, CX, NDEx, SQL, and Neo4J.

Its companion package, PyBEL Tools, contains a suite of functions and pipelines for analyzing the resulting biological networks.

We realize there we have a name conflict with the python wrapper for the cheminformatics package, OpenBabel. If you’re looking for their python wrapper, see here.

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Citation

If you use PyBEL in your work, please cite:

[1]Hoyt, C. T., et al. (2017). PyBEL: a Computational Framework for Biological Expression Language. Bioinformatics, 34(December), 1–2.

Getting Started

This example illustrates how the Selventa Small Corpus can be loaded and visualized in a Jupyter Notebook. Note that this requires an extension, the pybel-jupyter repository. This is not included by default because installing the Jupyter and iPython stack has a large footprint.

>>> import pybel, pybel_jupyter
>>> graph = pybel.from_url('http://resources.openbel.org/belframework/20150611/knowledge/small_corpus.bel')
>>> graph.number_of_nodes()  # Will be smaller than expected because we have the most strict settings enabled
1207
>>> pybel_jupyter.to_jupyter(graph)  # Need to pip install pybel-jupyter first

More examples can be found in the documentation and in the PyBEL Notebooks repository.

PyBEL also installs a command line interface with the command pybel for simple utilities such as data conversion. In this example, a BEL Script is exported to GraphML for viewing in Cytoscape.

$ pybel convert --path ~/Desktop/example.bel --graphml ~/Desktop/example.graphml

In Cytoscape, open with Import > Network > From File.

Installation Current version on PyPI Stable Supported Python Versions Apache 2.0 License

PyBEL can be installed easily from PyPI with the following code in your favorite terminal:

$ python3 -m pip install pybel

or from the latest code on GitHub with:

$ python3 -m pip install git+https://github.com/pybel/pybel.git@develop

See the installation documentation for more advanced instructions. Also, check the change log at CHANGELOG.rst.

Contributing

Contributions, whether filing an issue, making a pull request, or forking, are appreciated. See CONTRIBUTING.rst for more information on getting involved. Please add your name to AUTHORS.rst!

Acknowledgements

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