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Fast ARG normalization by mapping to the ARO ontology.

Project description

argNorm

Python package Downloads

Fast antibiotic resistance gene (ARG) normalization by mapping to the antibiotic resistance ontology (ARO) by CARD.

This is a very-first implementation (not ready for production), but you're welcomed to try it and provide feedback to make it better.

We welcome your feedback on the Issues Page.

Supported databases

Installation

pip install argnorm

Basic usage

Use argnorm -h to see available options.

argnorm [database] -i [original_annotation.tsv] -o [annotation_result_with_aro.tsv]

Examples

Handling hamronized inputs.

argnorm deeparg -i examples/hamronized/deeparg.deeparg.orfs.tsv -o tmp
argnorm megares -i examples/hamronized/abricate.megares.tsv -o tmp
argnorm argannot -i examples/hamronized/abricate.argannot.tsv -o tmp
argnorm resfinder -i examples/hamronized/abricate.resfinder.tsv -o tmp
argnorm ncbi -i examples/hamronized/abricate.ncbi.tsv -o tmp

Handling raw inputs (not hamronized by hAMRonization)

argnorm deeparg -i examples/hamronized/deeparg.deeparg.orfs.tsv -o tmp
argnorm megares -i examples/hamronized/abricate.megares.tsv -o tmp  # tested
argnorm argannot -i examples/hamronized/abricate.argannot.tsv -o tmp
argnorm resfinder -i examples/hamronized/abricate.resfinder.tsv -o tmp
argnorm ncbi -i examples/hamronized/abricate.ncbi.tsv -o tmp  # tested

Maintainers

Name Email Organization
Hui Chong huichong.me@gmail.com Research Assistant, Big Data Biology Lab, Fudan University
Svetlana Ugarcina Perovic svetlana.ugarcina@gmail.com Postdoc Researcher, Big Data Biology Lab, Fudan University
Luis Pedro Coelho luis@luispedro.org Principle Investigator, Big Data Biology Lab, Fudan University

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