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A comprehensive toolkit for alternative splicing analysis

Project description

What is ASTK?

ASTK is a command-line software for comprehensive alternative splicing analysis including:

  • characterizing distribution and expression patterns of alternative splicing events
  • systematically analyzing functional effects of AS events at the gene- and exon-level respectively
  • dissecting out splicing-associated sequence features and epigenetic marks
  • inferring the splicing regulatory code for each type of AS.

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Documentation

The documentation for ASTK is available on astk-doc.

How to cite

Huang, S., He, J., Yu, L., Guo, J., Jiang, S., Sun, Z., Cheng, L., Chen, X., Ji, X. and Zhang, Y. (2024), ASTK: A Machine Learning-Based Integrative Software for Alternative Splicing Analysis. Adv. Intell. Syst. 2300594. https://doi.org/10.1002/aisy.202300594

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