BETSEE, the BioElectric Tissue Simulation Engine Environment.
BETSEE (BioElectric Tissue Simulation Engine Environment) is the open-source cross-platform graphical user interface (GUI) for BETSE, a finite volume simulator for 2D computational multiphysics problems in the life sciences – including electrodiffusion, electro-osmosis, galvanotaxis, voltage-gated ion channels, gene regulatory networks, and biochemical reaction networks (e.g., metabolism).
BETSEE is universally installable with either:
[Recommended] pip, the standard Python package manager:
pip3 install betsee
Anaconda, a third-party Python package manager:
conda config --add channels conda-forge conda install betsee
Alexis Pietak and Michael Levin, 2016. Exploring instructive physiological signaling with the bioelectric tissue simulation engine (BETSE). (Supplement).  Frontiers in Bioengineering and Biotechnology, 4(55). https://doi.org/10.3389/fbioe.2016.00055
See also this list of BETSE-centric papers for additional material.
BETSEE is currently independently financed as a volunteer open-source project. Prior grant funding sources include (in chronological order):
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