Skip to main content

BHMM: A toolkit for Bayesian hidden Markov model analysis of single-molecule trajectories.

Project description

This project provides tools for estimating the number of metastable states, rate constants between the states, equilibrium populations, distributions characterizing the states, and distributions of these quantities from single-molecule data. This data could be FRET data, single-molecule pulling data, or any data where one or more observables are recorded as a function of time. A Hidden Markov Model (HMM) is used to interpret the observed dynamics, and a distribution of models that fit the data is sampled using Bayesian inference techniques and Markov chain Monte Carlo (MCMC), allowing for both the characterization of uncertainties in the model and modeling of the expected information gain by new experiments.

Project details


Download files

Download the file for your platform. If you're not sure which to choose, learn more about installing packages.

Source Distribution

bhmm-0.6.3.tar.gz (318.9 kB view hashes)

Uploaded source

Supported by

AWS AWS Cloud computing Datadog Datadog Monitoring Facebook / Instagram Facebook / Instagram PSF Sponsor Fastly Fastly CDN Google Google Object Storage and Download Analytics Huawei Huawei PSF Sponsor Microsoft Microsoft PSF Sponsor NVIDIA NVIDIA PSF Sponsor Pingdom Pingdom Monitoring Salesforce Salesforce PSF Sponsor Sentry Sentry Error logging StatusPage StatusPage Status page