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# Datasets

We provide scripts for downloading IU X-ray and Peir Gross. Both datasets can be used for captioning, while IU X-ray can also be used for tagging.

#### IU X-ray

IU X-ray (Demner-Fushman et al., 2015) is provided by the Open Access Biomedical Image Search Engine (OpenI) and it consists of radiology examinations (cases). Each case corresponds to one or more images, one radiology report and two sets of tags. The reports have 4 sections: Comparison, Indication, Findings and Impression, of which Findings and Impression can be used for captioning. There are two types of tags: the MTI tags, which are extracted from the text by the Medical Text Indexer and the manual tags, which are assigned by two trained coders. In total, there are 3,955 reports with 7,470 frontal and lateral X-rays.

#### Peir Gross

This dataset was first used for captioning by Jing et al. (2018). It consists of photographs of medical incidents provided by the Pathology Education Informational Resource (PEIR) digital library for use in medical education. There are 7,443 images extracted from the Gross collections of 21 PEIR pathology sub-categories, each associated with a caption. Each caption is a single descriptive sentence.

# Tagging

#### Mean@k-NN

Mean@k-NN uses an image retrieval method to assign tags to images by computing cosine similarities between image embeddings. Given a test image, this system retrieves the k most similar training images and their tags. The most frequent tags of the retrieved images are assigned to the test image. The average number of tags per retrieved image is calculated to decide how many tags will be assigned to the test image. The value of k is tuned on validation data.

#### TagCXN (also called ConceptCXN)

This system performs multi-label classification. It uses the DenseNet-121 CNN as an image encoder. The image embeddings are extracted from the last average pooling layer of the encoder and passed through a dense layer that produces a probability for each tag. At test time, first, the threshold that is used to assign tags to an image is tuned on validation data. Then, the tags that have a probability that exceeds the resulting threshold are assigned to each test image.

# Captioning

#### Frequency Baseline

This baseline uses the most frequent words in the training set to form a caption. This caption is then assigned to every test image. The length of the caption is the average length of the training captions.

#### Nearest Neighbour Baseline (1-NN)

1-NN uses cosine similarity to find the training image that is the most similar to a test image and assigns the retrieved training caption to the test image. The images are encoded by a CNN and their image embedding extracted from a layer of the encoder is used.

The datasets and captioning models are described in detail in "A Survey on Biomedical Image Captioning". The tagging models were used for the participation of AUEB NLP Group in the ImageCLEFmed 2019 Concept Prediction task, where they achieved the best performance. More detail can be found in the systems description paper.

#### References

V. Kougia, J. Pavlopoulos and I. Androutsopoulos, "A Survey on Biomedical Image Captioning". Proceedings of the Workshop on Shortcomings in Vision and Language of the Annual Conference of the North American Chapter of the Association for Computational Linguistics (NAACL-HLT 2019), Minneapolis, USA, pp. 26-36, 2019.

V. Kougia, J. Pavlopoulos and I. Androutsopoulos, "AUEB NLP Group at ImageCLEFmed Caption 2019". Working Notes of the Conference and Labs of the Evaluation Forum (CLEF 2019), Lugano, Switzerland, 2019.

B. Jing, P. Xie, E. Xing, “On the Automatic Generation of Medical Imaging Reports”. Proceedings of the 56th Annual Meeting of the Association for Computational Linguistics(Long Papers), Melbourne, Australia, pp. 2577–2586, 2018.

D. Demner-Fushman, M. D. Kohli, M. B. Rosenman,S. E. Shooshan, L. Rodriguez, S. Antani, G. R.Thoma, and C. J. McDonald, “Preparing a collection of radiology examinations for distribution and retrieval”. Journal of the American Medical In-formatics Association, 23(2):304–310, 2015.

# Practical Guide

### Install

To install the package

pip install bioCaption


### Mecical Image Captioning

#### How to use

from bioCaption.data.downloads import DownloadData
from bioCaption.models.captionModels.baselines import Baselines
from bioCaption.models.captionModels.caption_models_evaluation import CaptionsEvaluation

baselines = Baselines('iu_xray/train_images.tsv','iu_xray/test_images.tsv','iu_xray/iu_xray_images/','results')
baselines.most_frequent_word_in_captions()

evaluation = CaptionsEvaluation('iu_xray/test_images.tsv', 'results/most_frequent_word_results.tsv')

# if the directory "embeddings" does not exits, it will be created
evaluation.compute_WMD('embeddings/', embeddings_file="pubmed2018_w2v_200D.bin")
evaluation.compute_ms_coco()


You'll need to provide two tsv files, one for training and one for testing. The dataset needs to have the following syntax:

img_id_11,img_id_12,img_id13   caption1
img_id21 caption2
img_id31,img_31 caption3

• There are no spaces after each comma.
• Between the image ids and the caption there's a tab (/t).
• Each img_id corresponds to an actual image name stored separately into an image's folder.

#### Results

Results are saved in the 'results' folder, in a tsv file with the form.

{
"imgid1,imgid2": "caption1",
"imgid3": "caption2",
"imgid4,imgid5": "caption3"
}


### Medical Image Tagging

#### K-NN

from bioCaption.data.downloads import DownloadData
from bioCaption.models.tagModels.knn import Knn

knn = Knn('iu_xray/tags.json', 'iu_xray/iu_xray_images/', 'results_tag')
best_k = knn.knn()
knn.test(best_k)


#### cheXNet

from bioCaption.data.downloads import DownloadData
from bioCaption.models.tagModels.chexnet import Chexnet

"""
Load data and split the into train, test and
evaluation according to the split ratio.
"""
chexnet = Chexnet('iu_xray/tags.json',
'iu_xray/iu_xray_images/',
'results_tag',
split_ratio = [0.6, 0.3, 0.1])

"""
Train the model and checkpoint to model_path.
"""
chexnet.chexnet(batch_size=2, epochs=2, model_path='iu_xray')

""" While training, chexnet saves the model into the
instance variable "chexnet.model". If "model_path" is None
the model stored into chexnet.model is used else
there's an attempt to load the model from the "model path"
"""
chexnet.chexnet_test(decision_threshold=0.5, model_path=None)


#### Input data file.

{
"imgid1": ["tag1", "tag2", "tag3"],
"imgid2": ["tag1", "tag2"],
"imgid3": ["tag1"]
}

• Each img_id corresponds to an actual image name stored separately into an image's folder.

#### Results

{
"imgid1": ["tag1", "tag2", "tag3"],
"imgid2": ["tag1", "tag2"],
"imgid3": ["tag1"]
}


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