Change-O - Repertoire clonal assignment toolkit
Change-O is a collection of tools for processing the output of V(D)J alignment tools, assigning clonal clusters to immunoglobulin (Ig) sequences, and reconstructing germline sequences.
Dramatic improvements in high-throughput sequencing technologies now enable large-scale characterization of Ig repertoires, defined as the collection of trans-membrane antigen-receptor proteins located on the surface of B cells and T cells. Change-O is a suite of utilities to facilitate advanced analysis of Ig and TCR sequences following germline segment assignment. Change-O handles output from IMGT/HighV-QUEST and IgBLAST, and provides a wide variety of clustering methods for assigning clonal groups to Ig sequences. Record sorting, grouping, and various database manipulation operations are also included.
IMPORTANT! Active development of Change-O has moved to https://github.com/immcantation/changeo
6 maintainers
Download files
Download the file for your platform. If you're not sure which to choose, learn more about installing packages.
Source Distribution
File details
Details for the file changeo-1.3.5.tar.gz.
File metadata
- Download URL: changeo-1.3.5.tar.gz
- Upload date:
- Size: 165.3 kB
- Tags: Source
- Uploaded using Trusted Publishing? No
- Uploaded via:
twine/6.2.0 CPython/3.14.7
File hashes
| Algorithm | Hash digest | |
|---|---|---|
| SHA256 |
a15b58cce45bcbe2d0de1c3faf49f76d38fafdaca25c07d7de90e13c8ebe28ed
|
|
| MD5 |
7ac43972ccdba1de30d588f184988a83
|
|
| BLAKE2b-256 |
7688c16d5cce10c5107dc85e154cd2e6995569aa6d3c906f2b553ec16373db31
|
