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A contig binning tool from viral metagenomes

Project description

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Citation (Work in progress)

Arisdakessian C., Nigro O., Steward G., Poisson G., Belcaid M. Binning viral metagenomes using a deep neural network

Description

CoCoNet (Composition and Coverage Network) is a binning method for viral metagenomes. It leverages deep learning to abstract the modeling of the k-mer composition and the coverage for binning contigs assembled form viral metagenomic data. Specifically, our method uses a neural network to learn from the metagenomic data a flexible function for predicting the probability that any pair of contigs originated from the same genome. These probabilities are subsequently combined to infer bins, or clusters representing the species present in the sequenced samples. Our approach was specifically designed for diverse viral metagenomes, such as those found in environmental samples (e.g., oceans, soil, etc.).

Install

CoCoNet is available on PyPi and can be installed with pip:

pip3 install coconet-binning --user

Basic usage

CoCoNet is available as the command line program. For a list of all the options, open a terminal and run:

coconet -h

For more details, please see the documentation on ReadTheDocs

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