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CRNT4SBML is an easily installable Python based package available on Mac and Windows. CRNT4SBML is concentrated on providing a simple workflow for the testing of core CRNT methods directed at detecting bistability in cell signaling pathways endowed with mass action kinetics.

Project description

CRNT4SBML

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CRNT4SBML is an easily installable Python based package available on Mac and Windows. CRNT4SBML is concentrated on providing a simple workflow for the testing of core CRNT methods directed at detecting bistability in cell signaling pathways endowed with mass action kinetics.

Features

  • Routine for testing of the Deficiency Zero and One Theorems.

  • Routine for running the mass conservation approach.

  • Routine for running the semi-diffusive approach.

Credits

This package was created with Cookiecutter and the audreyr/cookiecutter-pypackage project template.

History

0.0.1 (08-22-2019)

  • First release on PyPI.

0.0.2 (08-23-2019)

  • Addition of Cytoscape functionality.

0.0.3 (08-26-2019)

  • Improvements to the plots produced by the continuity analysis.

0.0.4 (09-5-2019)

  • Addition of safety precautions for numerical continuation.

0.0.5 (09-16-2019)

  • Addition of routines to parse catalysis in SBML.

  • Addition of routines to automatically generate physiological bounds.

0.0.6 (09-23-2019)

  • Updating safety wrapper to smoothly work on Windows and Mac.

0.0.7 (10-11-2019)

  • Adding output to continuity routine to make post-processing simpler.

0.0.8 (10-23-2019)

  • Adding functionality to allow use of Jupyter notebooks.

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