Cycleenrichr uses PrismEXP predictions to calculate enrichment of gene sets that do not have gene annotations.
Project description
Cycle Enrichr
Enrichment of gene sets with no gene annotations leveraging ARCHS4 and PrismExp gene function prediction.
Usage
Installation
pip3 install cycleenrichr
Download Prediction File
# download precomputed predictions file from PrismExp
import cycleenrichr as cycle
cycle.load.download("predictions.h5")
Run Set Enrichment for Gene Set Library
import cycleenrichr as cycle
# load gene set libary from Enrichr
library = cycle.enrichr.get_library("KEGG_2021_Human")
predictions_path = "predictions.h5"
result = cycle.enrichment.enrich(library, predictions_path)
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