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CyLinter

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## An Interactive Image Segmentation Filter for Multiplex Microscopy.

CyLinter is quality control software for identifying and removing cell segmentation instances corrupted by optical and/or image-processing artifacts in multiplex microscopy images. The tool is user-guided and comprises a set of modular and extensible QC modules instantiated in a configurable [Python](https://www.python.org) Class object. Module results are cached to allow for dynamic restarts.

CyLinter development is led by [Greg Baker](https://github.com/gjbaker) at the [Laboratory of Systems Pharmacology](https://hits.harvard.edu/the-program/laboratory-of-systems-pharmacology/about/), Harvard Medical School.

Funding: This work is supported by the following:

  • NCI grant U2C-CA233262: Pre-cancer Atlases of Cutaneous and Hematologic Origin

  • NIH grant U54CA225088: Systems Pharmacology of Therapeutic and Adverse Responses to Immune Checkpoint and Small Molecule Drugs

  • Ludwig Center at Harvard Medical School and the Ludwig Cancer Research Foundation

Instructions: https://labsyspharm.github.io/cylinter/

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