Fast functional annotation of novel sequences using eggNOG orthology assignments.
Project description
Overview
EggNOG-mapper is a tool for fast functional annotation of novel sequences. It uses precomputed orthologous groups and phylogenies from the eggNOG database (http://eggnog5.embl.de) to transfer functional information from fine-grained orthologs only.
Common uses of eggNOG-mapper include the annotation of novel genomes, transcriptomes or even metagenomic gene catalogs.
The use of orthology predictions for functional annotation permits a higher precision than traditional homology searches (i.e. BLAST searches), as it avoids transferring annotations from close paralogs (duplicate genes with a higher chance of being involved in functional divergence).
Benchmarks comparing different eggNOG-mapper options against BLAST and InterProScan can be found here.
EggNOG-mapper is also available as a public online resource: http://eggnog-mapper.embl.de
Documentation
https://github.com/jhcepas/eggnog-mapper/wiki
Citation
If you use this software, please cite:
[1] Fast genome-wide functional annotation through orthology assignment by
eggNOG-mapper. Jaime Huerta-Cepas, Kristoffer Forslund, Luis Pedro Coelho,
Damian Szklarczyk, Lars Juhl Jensen, Christian von Mering and Peer Bork.
Mol Biol Evol (2017). [doi:
10.1093/molbev/msx148](https://doi.org/10.1093/molbev/msx148)
[2] eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated
orthology resource based on 5090 organisms and 2502 viruses. Jaime
Huerta-Cepas, Damian Szklarczyk, Davide Heller, Ana Hernández-Plaza, Sofia
K Forslund, Helen Cook, Daniel R Mende, Ivica Letunic, Thomas Rattei, Lars
J Jensen, Christian von Mering, Peer Bork Nucleic Acids Res. 2019 Jan 8;
47(Database issue): D309–D314. doi: 10.1093/nar/gky1085
Project details
Release history Release notifications | RSS feed
Download files
Download the file for your platform. If you're not sure which to choose, learn more about installing packages.
Source Distribution
Built Distribution
Hashes for eggnog-mapper-2.1.4.post2.tar.gz
Algorithm | Hash digest | |
---|---|---|
SHA256 | bd708ab2dd171d06404e783f819f276d070a1f898a3af2a11aa60a4366403773 |
|
MD5 | d6010b982fe6fafe49dcee307ab3e44e |
|
BLAKE2b-256 | 7abf0f09885116912bd279646a7e4c4e6ebe410d4ce178d6a4d4b46ad43f0ce7 |
Hashes for eggnog_mapper-2.1.4.post2-py3-none-any.whl
Algorithm | Hash digest | |
---|---|---|
SHA256 | 4137f014a27bd023cde92875447885ae93b78c2403f41cf1e56fb66adf4067c2 |
|
MD5 | 200a1c002451946a3aea007645f32c39 |
|
BLAKE2b-256 | f8eef74daad4ba24380b9eb0cd5191ab094b29a3aeea3d27c5afbe9456f6de77 |