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Fast and flexible inference of the distribution of fitness effects (DFE), VCF-SFS parsing with ancestral allele and site-degeneracy annotation.

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fastDFE

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fastdfe is a package for fast, flexible, and hierarchical inference of the distribution of fitness effects (DFE) from site frequency spectra (SFS). It also contains a versatile VCF-to-SFS parser with support for ancestral allele and site-degeneracy annotation.

Please see the documentation for all the details.

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