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FRAMED - FRAmework for Metabolic Engineering and Design

Project description

FRAMED is a python package for analysis and simulation of
metabolic models. It is continuously under development. Some of the current
functionality includes:

- Import/Export of SBML files (constraint-based and kinetic models)
- Import/Export from plain text (constraint-based only)
- Simulation methods: FBA, pFBA, MOMA, linearMOMA, ROOM, loopless-FBA,
dynamicFBA (single and multi-species)
- Analysis tools: FVA, PhPP, production envelope plotting, gene
essentiality analysis
- Reconstruction: gapFind, gapFill
- Rational strain design: combinatorial, greedy (gene and
- Omics integration: GIMME, E-Flux
- Kinetic models (experimental support): time-course and steady-state
simulation, sampling, plotting utils

Credits and License

Developed at:

- The Novo Nordisk Fundation Center for Biosustainability

- Centre of Biological Engineering, University of Minho

- European Molecular Biology Laboratory (2016)

Released under an Apache License.

Project details

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