Golden Hinges
Golden Hinges (full documentation here) is a Python library to find sets of overhangs (also called junctions, or protrusions) for multipart DNA assembly such as Golden Gate assembly.
Given a set of constraints (GC content bounds, differences between overhangs, mandatory and forbidden overhangs) Golden Hinges enables to find:
Maximal sets of valid and inter-compatible overhangs.
Sequence decompositions (i.e. position of cuts) which produce valid and inter-compatible overhangs, for type-2S DNA assembly.
Sequence mutations (subject to constraints) which enable the sequence decomposition, in extreme cases where the original sequence does not allow for such decomposition.
Infos
PIP installation:
pip install goldenhingesWeb documentation:
https://edinburgh-genome-foundry.github.io/GoldenHinges/
Github Page (with examples)
https://github.com/Edinburgh-Genome-Foundry/GoldenHinges
Live demo:
http://cuba.genomefoundry.org/design_overhangs
License: MIT, Copyright Edinburgh Genome Foundry
More biology software
Golden Hinges is part of the EGF Codons synthetic biology software suite for DNA design, manufacturing and validation.
1 maintainer
Metadata
1 maintainer
Release files for goldenhinges 0.2.3
For a detailed explanation of source distributions (sdists) and built distributions (wheels), please see the package formats documentation.
Source distribution (sdist)
| File | Size | Uploaded | |
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| goldenhinges-0.2.3.tar.gz | 39.9 kB | Details |
Built distribution (wheel)
| File | Interpreter | ABI | Platform | Reset |
|---|---|---|---|---|
| goldenhinges-0.2.3-py3-none-any.whl | Python 3 | none | any | Details |
Total release size: 58.5 kB
Release files / goldenhinges-0.2.3.tar.gz
| Download URL | goldenhinges-0.2.3.tar.gz |
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| Size | 39.9 kB |
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Release files / goldenhinges-0.2.3-py3-none-any.whl
| Download URL | goldenhinges-0.2.3-py3-none-any.whl |
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| Size | 18.6 kB |
| Tags | Python 3 |
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