Skip to main content

Interface to the image correlation spectroscopy library ICSx64.dll

Project description

ICSdll is a Python/ctypes interface to the Image Correlation Spectroscopy Dynamic Link Library (ICSx64.dll) developed at the Laboratory for Fluorescence Dynamics (LFD) for the Globals for Images SimFCS software.

ICSx64.dll is implemented in C++ using the Intel(r) Math Kernel Library and OpenMP. It provides functions and classes for the analysis of fluorescence time series data:

  • 1D, 2D, and 3D auto- and cross-correlation

  • Image pair correlation function (ipCF)

  • Airy detector pair correlation function (apCF)

  • Image mean square displacement (iMSD)

  • Line spatio-temporal image correlation spectroscopy (lSTICS)

  • Fit 1D pair correlation functions to the results of ipCF analysis

  • Subtract immobile fractions

  • Correct photo-bleaching


Christoph Gohlke


Laboratory for Fluorescence Dynamics. University of California, Irvine


3-clause BSD






Pass 22 tests. Wrap apcf, imsd, and lstics functions. Raise IcsError in case of DLL function errors. Use ICSx64.DLL version 2019.7.10.


Initial release based on ICSx64.DLL version 2018.7.18.


ICSdll is currently developed, built, and tested on 64-bit Windows only.

The API is not stable and might change between revisions.

Refer to the C++ header file and source code for function signatures.


  1. ipcf.ipynb Pair correlation function analysis of fluorescence fluctuations in big image time series using Python.

  2. Globals for Images SimFCS, Software for fluorescence image acquisition, analysis, and simulation.

  3. Globals for Airyscan, Image correlation analysis for the ZEISS(tm) LSM 880 Airyscan detector.

Project details

Download files

Download the file for your platform. If you're not sure which to choose, learn more about installing packages.

Source Distributions

No source distribution files available for this release. See tutorial on generating distribution archives.

Built Distributions

icsdll-2019.7.10-cp38-cp38m-win_amd64.whl (15.2 MB view hashes)

Uploaded cp38

icsdll-2019.7.10-cp37-cp37m-win_amd64.whl (15.2 MB view hashes)

Uploaded cp37

icsdll-2019.7.10-cp36-cp36m-win_amd64.whl (15.2 MB view hashes)

Uploaded cp36

icsdll-2019.7.10-cp35-cp35m-win_amd64.whl (15.2 MB view hashes)

Uploaded cp35

Supported by

AWS AWS Cloud computing Datadog Datadog Monitoring Facebook / Instagram Facebook / Instagram PSF Sponsor Fastly Fastly CDN Google Google Object Storage and Download Analytics Huawei Huawei PSF Sponsor Microsoft Microsoft PSF Sponsor NVIDIA NVIDIA PSF Sponsor Pingdom Pingdom Monitoring Salesforce Salesforce PSF Sponsor Sentry Sentry Error logging StatusPage StatusPage Status page