in-silico-cancer-cell 0.2.3

Simulation of an electrophysiological A549 cancer cell model using individual ion channels across the membrane

Electrophysiological Cancer Cell Model

Attempt to model an A549 cancer cell's ion channels using an HMM (Hidden Markov Model) and simulation of voltage + current development accross the membrane of the cell.

This software comes in three flavours:

• to run the main.rs simulation, do cargo run,
• to compile the Python module, do maturin develop --features pyo3,
• to precompile for the Astro dashboard, do yarn run wasm-pack build frontend.

A visual to capture your interest:

(Image source: here).

This computational model is based on Langthaler et al., 2021: A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma.

The Simulation Dashboard