metapub 0.3.14.3.3

Pubmed / NCBI / eutils interaction library, handling the metadata of pubmed papers.

Metapub is a Python library that provides python objects fetched via eutils that represent papers and concepts found within the NLM.

These objects abstract some interactions with pubmed, and intends to encompass as many types of database lookups and summaries as can be provided via Eutils / Entrez.

PubMedArticle / PubMedFetcher

Basic usage:

fetch = PubMedFetcher()
article = fetch.article_by_pmid('123456')
print article.title
print article.journal, article.year, article.volume, article.issue
print article.authors

PubMedFetcher uses an SQLite cacheing engine (provided through eutils), which by default places a file in your user directory. E.g. the author’s cache directory path would be /home/nthmost/.cache/eutils-cache.db

This cache file can grow quite large over time. Deleting the cache file is safe and can also be regarded as the way to “reset” the cache.

The cachedir keyword argument can be supplied to PubMedFetcher as a way to specify where the cache file will reside. For example:

fetch = PubMedFetcher(cachedir='/path/to/cachedir')

User directory expansion also works:

fetch = PubMedFetcher(cachedir=’~/.othercachedir’)

The cachedir will be created for you if it doesn’t already exist, assuming the user account you’re running metapub under has permissions to do so.

PubMedArticle Lookup Methods

The following methods return a PubMedArticle object (or raise InvalidPMID if NCBI lookup fails).

article_by_pmid

(Attempt to) fetch an article by supplying its pubmed ID (both integer and string accepted).

article_by_doi

(Attempt to) fetch an article by looking up the DOI first.

article_by_pmcid

Fetch an article by looking up the PMCID first. Both integer and string accepted.

Pubmed ID List Methods

The following methods return a list of pubmed IDs (if found) or an empty list (if None).

pmids_from_citation

Produces a list of possible PMIDs for the submitted citation, where the citation is submitted as a collection of keyword arguments. At least 3 of the 5, preferably 4 or 5 for best results, must be included:

aulast or author_last_fm1
year
volume
first_page or spage
journal or jtitle

Use NLM Title Abbreviation (aka ISO Abbreviation) journal strings whenever possible.

pmids_for_query

Returns list of pmids for given freeform query string plus keyword arguments.

All Pubmed Advanced Query tokens are supported.

See [NCBI Search Field Descriptions and Tags](http://www.ncbi.nlm.nih.gov/books/NBK3827/)

pmids_for_clinical_query

Composes a “Clinical Query” as on this page: (http://www.ncbi.nlm.nih.gov/pubmed/clinical/)

Supply a “category” (required) and an optimization (“broad” or “narrow”) for this function. Available categories:

• therapy

• diagnosis

• etiology

• prognosis

• prediction

All keyword arguments for PubMedFetcher.pmids_for_query available.

pmids_for_medical_genetics_query

Composes a “Medical Genetics Query” as described here: (http://www.ncbi.nlm.nih.gov/books/NBK3827/#pubmedhelp.Medical_Genetics_Search_Filte)

Supply a “category” (required) and an optimization (“broad” or “narrow”) for this function. Available categories:

• therapy

• diagnosis

• etiology

• prognosis

• prediction

All keyword arguments for PubMedFetcher.pmids_for_query available.

metapub.pubmedcentral.*

The PubMedCentral functions are a loose collection of conversion methods for academic publishing IDs, allowing conversion (where possible) between the following ID types:

doi (Digital object identifier)
pmid (PubMed ID)
pmcid (Pubmed Central ID (including versioned document ID)

The following methods are supplied, returning a string (if found) or None:

get_pmid_for_otherid(string)
get_doi_for_otherid(string)
get_pmcid_for_otherid(string)

As implied by the function names, you can supply any valid ID type (“otherid”) to acquire the desired ID type.

MedGenConcept / MedGenFetcher

Basic usage:

fetch = MedGenFetcher()
concept = fetch.concept_by_uid('336867')
print concept.name
print concept.description
print concept.associated_genes
print concept.modes_of_inheritance

CrossRef

The CrossRef object provides an object layer into search.crossref.org’s API. See http://search.crossref.org

CrossRef excels at resolving DOIs into article citation details.

CrossRef can also be used to resolve a DOI /from/ article citation details, with a bit of finagling. The “get_top_result” function was built to do some light interpretation of the json-based results of a CrossRef lookup.

Result scores under 2.0 are usually False matches. Result scores over 3.0 are always (?) True. Between 2.0 and 3.0 is a grey area: be wary and check results against any known info you may have.

Current testing (as of 1/23/2015) indicates that a cleverly-formed CrossRef query can return results 99% correct about 90% of the time.

The more params submitted with the query, the more accurate the results may be.

Basic usage:

CR = CrossRef()       # starts the query cache engine
results = CR(search_string, params)
top_result = CR.get_top_result(results)

Example starting from a known pubmed ID:

pma = PubMedFetcher().article_by_pmid(known_pmid)
results = CR.query_from_PubMedArticle(pma)
top_result = CR.get_top_result(results, CR.last_params, use_best_guess=True)

NOTE: if you don’t supply “CR.last_params”, you can’t use the “use_best_guess” operator. In cases where all results have scores under 2, no results will be returned unless use_best_guess=True. That’s often desired behavior, since results with scores under 2 are usually pretty bad.

As with the PubMedFetcher object, you can configure where the cache file ends up on the filesystem via the cachedir keyword argument.

Miscellaneous Utilities

Currently underdocumented utilities that you might find useful.

In metapub.utils:

• asciify (nuke all the unicode from orbit; it’s the only way to be sure)

• parameterize (make strings suitable for submission to GET-based query service)

• deparameterize (somewhat-undo parameterization in string)

• remove_html_markup (remove html and xml tags from text. preserves HTML entities like &)

In metapub.text_mining:

• find_doi_in_string (returns the first seen DOI in the input string)

• findall_dois_in_text (returns all seen DOIs in input string)

• pick_pmid (return longest numerical string from text (string) as the pmid)

In metapub.convert:

• PubMedArticle2doi (uses CrossRef to find a DOI for given PubMedArticle object.)

• pmid2doi (returns first found doi for pubmed ID “by any means necessary.)

• doi2pmid (uses CrossRef and eutils to return a PMID for given DOI if possible.)

More Information

Digital Identifiers of Scientific Literature: what they are, when they’re used, and what they look like.

http://www.biosciencewriters.com/Digital-identifiers-of-scientific-literature-PMID-PMCID-NIHMS-DOI-and-how-to-use-them.aspx

About, and a Disclaimer

Metapub relies on the very neat eutils package created by Reece Hart, which you can check out here:

http://bitbucket.org/biocommons/eutils

This library is in its very early stages and there’s a lot that may change, and quite a bit planned for implementation in 2015.

Feel free to use the library with confidence that each released version is well tested – and in a couple of cases, some of its code is already in production – but until (say) version 0.5, don’t expect consistency between versions.

YMMV, At your own risk, etc.

–Naomi Most (@nthmost)