Skip to main content

NeatBio - a simple Yet Another BioInformatics Library for DNA Sequence

Project description

neatbio

A Simple Yet Another Bioinformatics Library for DNA,RNA and Protein Sequencing

Installation

pip install neatbio

Benefits

  • Handling Sequences(DNA,RNA,Protein)
  • Protein Synthesis
  • Sequence Similarity
  • Kmers Generation and Kmer Distance
  • Probable Back Translation of Amino Acids
  • Reading FASTA files

Why NeatBio?

  • NeatBio is yet another bioinformatics library along side powerful and popular bioinformatics libraries such as biopython,scikit-bio,biotite.
  • It is meant to complement these powerful library in a simple way.

Usage

Handling Sequences

  • Neatbio offers the ability to analyse sequences for more insight
>>>import neatbio as nt
>>> seq1 = nt.Sequence('ATGCATTGA')
>>> seq1.gc
33.33333333333333
>>> seq1.gc_frequency()
3
>>> seq1.at
66.66666666666666
>>> seq1.at_frequency()
6
>>> seq1.transcribe()
'AUGCAUUGA'
>>> mrna = seq1.transcribe()
>>> nt.Sequence(mrna).back_transcribe()
'ATGCATTGA'
>>> 

>>> seq1.translate()
'MH*'
>>> seq1.translate
>>>
>>> rna_seq = nt.Sequence("AUGCAUUGA","RNA")
>>> rna_seq.seqtype
>>> Sequence(seq='AUGCAUUGA',seqtype='RNA')

Working with Proteins

>>> protein1 = nt.ProteinSeq('MIT')
>>> protein1
ProteinSeq(seq='MIT')
>>> protein1.back_translate()
'ATGATAACT'
  • Note that the back_translate() function offers a probable sequence and not the exact back-translation as multiple codons can represent the same amino acids.

Convert 3 Letter Amino Acid to 1 and vice versa

>>> from neatbio.sequtils import convert_3to1,convert_1to3,get_acid_name
>>> convert_3to1('Ala')
'A'
>>> convert_1to3('L')
'Leu'

>>> get_acid_name('Ala')
'Alanine'

Generate DotPlot

>>> import neatbio as nt 
>>> import neatbio.sequtils as utils
>>> seq1 = nt.Sequence('AGTCGTACT')
>>> seq2 = nt.Sequence('AGGCGCACT')
>>> 
>>> utils.dotplot(seq1,seq2)
 |AGGCGCACT
-----------
A|       
G| ■■     
T|        
C|      
G| ■■     
T|        
A|       
C|      
T|        
>>> 

Reading FASTA Files

>>> import neatbio as nt 
>>> file1 = nt.read_fasta('sequence.fasta')
>>> file1['seqRecord']


>>> seq1 = nt.Sequence(file1['seqRecord'])

Documentation

  • Please read the documentation for more information on what neatbio does and how to use is for your needs.

More Features To Add

  • sequence alignment
  • writing FASTA files
  • support for more file formats

Acknowledgements

  • Inspired by packages like BioPython,Scikit-Bio and Biotite

NB

  • Contributions Are Welcomed
  • Notice a bug, please let us know.
  • Thanks A lot

By

  • Jesse E.Agbe(JCharis)
  • Jesus Saves @JCharisTech

Project details


Download files

Download the file for your platform. If you're not sure which to choose, learn more about installing packages.

Source Distribution

neatbio-0.0.2.tar.gz (12.6 kB view details)

Uploaded Source

Built Distribution

neatbio-0.0.2-py3-none-any.whl (12.6 kB view details)

Uploaded Python 3

File details

Details for the file neatbio-0.0.2.tar.gz.

File metadata

  • Download URL: neatbio-0.0.2.tar.gz
  • Upload date:
  • Size: 12.6 kB
  • Tags: Source
  • Uploaded using Trusted Publishing? No
  • Uploaded via: poetry/1.0.5 CPython/3.6.9 Linux/5.3.0-51-generic

File hashes

Hashes for neatbio-0.0.2.tar.gz
Algorithm Hash digest
SHA256 a39f2ee6c7c7b8954e7016273d75779a0391836990cc8448fff05bdb232b6131
MD5 b9a5a88654298088ef93efaf7882ed15
BLAKE2b-256 f7335b5ceb5dd93e94ca94724e184a924ce11c34d0f412cdd9d1f74d3e3b5269

See more details on using hashes here.

File details

Details for the file neatbio-0.0.2-py3-none-any.whl.

File metadata

  • Download URL: neatbio-0.0.2-py3-none-any.whl
  • Upload date:
  • Size: 12.6 kB
  • Tags: Python 3
  • Uploaded using Trusted Publishing? No
  • Uploaded via: poetry/1.0.5 CPython/3.6.9 Linux/5.3.0-51-generic

File hashes

Hashes for neatbio-0.0.2-py3-none-any.whl
Algorithm Hash digest
SHA256 e78f9edf4963fde7363b5d7fce42824ff1070b26871a57344c520d8507492e5a
MD5 873831ce70eef14c4270d62b7deab0cb
BLAKE2b-256 49fc2ae3fe1bebfe51f7f19b94fe0fd76aca603955d174ab794b4bc1860df5a5

See more details on using hashes here.

Supported by

AWS AWS Cloud computing and Security Sponsor Datadog Datadog Monitoring Fastly Fastly CDN Google Google Download Analytics Microsoft Microsoft PSF Sponsor Pingdom Pingdom Monitoring Sentry Sentry Error logging StatusPage StatusPage Status page