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comprehensive neoepitope prediction software

Project description

neoepiscope is software for predicting neoepitopes from DNA sequencing (DNA-seq) data. Where most neoepitope prediction software confines attention to neoepitopes arising from at most one somatic mutation, often just an SNV, neoepiscope uses assembled haplotype output of HapCUT2 (Edge et al., 2017) to also enumerate neoepitopes arising from more than one somatic mutation. neoepiscope also takes into account frameshifting from indels and permits personalizing the reference transcriptome using germline variants.

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