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NicheCompass (Niche Identification based on Cellular grapH Embeddings of COMmunication Programs Aligned across Spatial Samples) is a package for end-to-end analysis of spatial multi-omics data, including spatial atlas building, niche identification & characterization, cell-cell communication inference and spatial reference mapping. It is built on top of PyG and AnnData.

Resources

  • An installation guide, tutorials and API documentation is available in the documentation.
  • Please use issues to submit bug reports.
  • If you would like to contribute, check out the contributing guide.
  • If you find NicheCompass useful for your research, please consider citing the NicheCompass manuscript.

Reference

@article{Birk2025,
  author    = {Birk, S. et al.},
  title     = {Quantitative characterization of cell niches in spatially resolved omics data},
  journal   = {Nature Genetics},
  year      = {2025},
  doi       = {10.1038/s41588-025-02120-6},
  url       = {https://doi.org/10.1038/s41588-025-02120-6}
}

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Release files for nichecompass 0.3.3

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This release

0.3.3 This release

2 release files

0.3.2

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0.3.1

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0.3.0

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0.2.4

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0.2.3

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0.2.1

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0.2.0

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0.1.3

2 release files

0.1.2

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