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De novo spatial reconstruction of single-cell gene expression.

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novoSpaRc - de novo Spatial Reconstruction of Single-Cell Gene Expression

novoSpaRc predicts locations of single cells in space by solely using single-cell RNA sequencing data. An existing reference database of marker genes is not required, but significantly enhances performance if available.

novoSpaRc accompanies the following publication:

Charting a tissue from single-cell transcriptomes
M. Nitzan, N. Karaiskos, N. Friedman, N. Rajewsky

Read the documentation for more information.

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