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A Python 3.6 library for plotting mutational spectra.

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Analysis and plotting library for base substitution spectra and signatures.

❯ pip install nucleic


  • Model DNA and variant alleles within their local context using an elegant API
  • Combine single nucleotide variants into spectrums of mutagenesis
  • Fetch COSMIC signatures of mutation as well as other published signatures
  • SVG plotting functions for displaying single nucleotide variant spectrums

Read the documentation at:

from nucleic import fetch_cosmic_signatures
from nucleic.figures import plot_stratton_spectrum

signatures = fetch_cosmic_signatures()
canvas, (ax1, ax2) = plot_stratton_spectrum(signatures['Signature 24'])


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