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Libraries and applications for working with calculated polygenic scores

Project description

pgscatalog.calc

Run pytest on pgscatalog.calc Documentation Status

This Python package contains:

  • CLI applications to aggregate and adjust calculated PGS in the context of genetic ancestry similarity
  • library classes and functions for working with calculated PGS and PCA data
Application Description Link
pgscatalog-aggregate Aggregate calculated PGS split across multiple files README
pgscatalog-ancestry-adjust Adjust calculated PGS in the context of genetic ancestry README

If you want to write Python code to work with PGS data, the library may be helpful for you.

Please note this package doesn't contain functionality to calculate a PGS from target genomes and scoring files. Instead, it's focused on aggregation and normalisation. If you want to do automatic PGS calculation check out the PGS Catalog Calculator, which uses these tools internally.

Installation

install with bioconda

or install via pip:

$ pipx install pgscatalog.calc

Documentation

Documentation is available at https://pygscatalog.readthedocs.io/.

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