pRESTO is a toolkit for processing raw reads from high-throughput sequencing of B cell and T cell repertoires.
Dramatic improvements in high-throughput sequencing technologies now enable large-scale characterization of lymphocyte repertoires, defined as the collection of trans-membrane antigen-receptor proteins located on the surface of B cells and T cells. The REpertoire Sequencing TOolkit (pRESTO) is composed of a suite of utilities to handle all stages of sequence processing prior to germline segment assignment. pRESTO is designed to handle either single reads or paired-end reads. It includes features for quality control, primer masking, annotation of reads with sequence embedded barcodes, generation of unique molecular identifier (UMI) consensus sequences, assembly of paired-end reads and identification of duplicate sequences. Numerous options for sequence sorting, sampling and conversion operations are also included.
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Release files for presto 0.5.10
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Source distribution (sdist)
| File | Size | Uploaded | |
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| presto-0.5.10.tar.gz | 99.2 kB | Details |
Release files / presto-0.5.10.tar.gz
| Download URL | presto-0.5.10.tar.gz |
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| Size | 99.2 kB |
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