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Inertial mass determination

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Welcome to pyIMD!

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Evolution of mass over time and the corresponding microscopy images are shown for a time span of 20min. The mass data was acquired every 10ms (data shown in black), overlaid in red is the rolling mean with a window of 1000. Images taken every 3 min over the observed times span, we see on average a steady increase of the cell mass.

With the introduction of a picoscopic cell balance that is compatible with optical microscopy, a new tool for the investigation of the cell state-dependent cell mass regulation is available for use in biophysics, cell biology, physiology and medicine. However, the analysis of the data can be challenging due to a) the amount of high resolution data or b) the structure of low-stress measurement (low resolution) data. Here, we introduce the software pyIMD, which allows to easily extract the mass as a function of time for non-moving cells out of the raw data. pyIMD Stands for Python inertial mass determination.

This documentation of pyIMD describes the API as well as gives provides a sample data set as well as sample scripts to run pyIMD from Jupyter or the Python console but it also contains a tutorial about how pyIMD is used with the user interface. The aim of this module is the calculation of the total/inertial mass for measurements taken in the continuous sweep or in the phase-lock loop (PLL) mode.

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