Python wrapper for the bwtool library.
Project description
Python wrapper for the bwtool library. Please take a look to the bwtool wiki for notes on the installation process and to the known issues listed below within this readme.
How do I install this package?
As usual, just download it using pip:
pip install pybwtool
Tests Coverage
Since some software handling coverages sometimes get slightly different results, here’s three of them:
Extract
The extract
method returns a tuple of pandas Dataframes
with the data from the regions of a bed file extracted from the given bigwig.
from pybwtool import extract bed, scores = extract( bed_path="path/to/my/bed_file.bed", bigwig_path="path/to/my/bigwig_file.bigwig" )
The obtained dataframes look as follows:
chrom | chromStart | chromEnd |
---|---|---|
chr11 | 14606206 | 14606406 |
chr1 | 1336296 | 1336496 |
chr11 | 47745644 | 47745844 |
chr11 | 62609072 | 62609272 |
chr14 | 21523971 | 21524171 |
0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 | 143 | 144 | 145 | 146 | 147 | 148 | 149 | 150 | 151 | 152 | 153 | 154 | 155 | 156 | 157 | 158 | 159 | 160 | 161 | 162 | 163 | 164 | 165 | 166 | 167 | 168 | 169 | 170 | 171 | 172 | 173 | 174 | 175 | 176 | 177 | 178 | 179 | 180 | 181 | 182 | 183 | 184 | 185 | 186 | 187 | 188 | 189 | 190 | 191 | 192 | 193 | 194 | 195 | 196 | 197 | 198 | 199 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0.22 | 0.22 | 0.21 | 0.22 | 0.21 | 0.22 | 0.24 | 0.25 | 0.28 | 0.28 | 0.26 | 0.26 | 0.26 | 0.26 | 0.26 | 0.31 | 0.31 | 0.31 | 0.32 | 0.33 | 0.33 | 0.33 | 0.32 | 0.35 | 0.36 | 0.36 | 0.36 | 0.36 | 0.36 | 0.36 | 0.37 | 0.37 | 0.36 | 0.37 | 0.37 | 0.37 | 0.36 | 0.32 | 0.32 | 0.32 | 0.33 | 0.33 | 0.33 | 0.33 | 0.35 | 0.35 | 0.35 | 0.35 | 0.35 | 0.35 | 0.36 | 0.39 | 0.39 | 0.37 | 0.37 | 0.36 | 0.35 | 0.33 | 0.31 | 0.31 | 0.29 | 0.29 | 0.29 | 0.29 | 0.29 | 0.25 | 0.24 | 0.28 | 0.26 | 0.25 | 0.25 | 0.25 | 0.24 | 0.19 | 0.18 | 0.18 | 0.17 | 0.17 | 0.18 | 0.19 | 0.18 | 0.18 | 0.18 | 0.17 | 0.18 | 0.18 | 0.18 | 0.18 | 0.18 | 0.18 | 0.17 | 0.24 | 0.25 | 0.25 | 0.24 | 0.22 | 0.22 | 0.25 | 0.25 | 0.25 | 0.24 | 0.21 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.24 | 0.24 | 0.24 | 0.26 | 0.26 | 0.26 | 0.26 | 0.26 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.21 | 0.21 | 0.21 | 0.19 | 0.19 | 0.19 | 0.22 | 0.22 | 0.22 | 0.22 | 0.24 | 0.25 | 0.25 | 0.26 | 0.26 | 0.26 | 0.19 | 0.18 | 0.18 | 0.18 | 0.18 | 0.18 | 0.15 | 0.15 | 0.15 | 0.15 | 0.15 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.18 | 0.17 | 0.17 | 0.17 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.18 | 0.18 | 0.18 | 0.18 | 0.18 | 0.15 | 0.15 | 0.15 | 0.14 | 0.12 | 0.11 | 0.12 | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 | 0.11 |
1.25 | 1.26 | 1.32 | 1.43 | 1.42 | 1.36 | 1.36 | 1.37 | 1.37 | 1.32 | 1.31 | 1.31 | 1.35 | 1.35 | 1.43 | 1.5 | 1.56 | 1.56 | 1.64 | 1.67 | 1.67 | 1.64 | 1.68 | 1.67 | 1.68 | 1.69 | 1.71 | 1.71 | 1.74 | 1.71 | 1.67 | 1.65 | 1.58 | 1.56 | 1.43 | 1.36 | 1.24 | 1.24 | 1.28 | 1.26 | 1.33 | 1.36 | 1.44 | 1.42 | 1.44 | 1.46 | 1.5 | 1.49 | 1.47 | 1.47 | 1.54 | 1.54 | 1.54 | 1.47 | 1.49 | 1.53 | 1.51 | 1.5 | 1.51 | 1.57 | 1.57 | 1.57 | 1.53 | 1.54 | 1.49 | 1.46 | 1.43 | 1.43 | 1.39 | 1.39 | 1.4 | 1.42 | 1.39 | 1.37 | 1.37 | 1.4 | 1.4 | 1.43 | 1.4 | 1.42 | 1.44 | 1.44 | 1.4 | 1.37 | 1.36 | 1.32 | 1.29 | 1.31 | 1.29 | 1.29 | 1.19 | 1.24 | 1.19 | 1.19 | 1.25 | 1.24 | 1.26 | 1.28 | 1.26 | 1.37 | 1.33 | 1.33 | 1.28 | 1.24 | 1.25 | 1.25 | 1.25 | 1.26 | 1.24 | 1.22 | 1.28 | 1.28 | 1.32 | 1.37 | 1.39 | 1.36 | 1.32 | 1.31 | 1.36 | 1.33 | 1.5 | 1.5 | 1.5 | 1.5 | 1.5 | 1.47 | 1.46 | 1.49 | 1.57 | 1.58 | 1.58 | 1.62 | 1.64 | 1.64 | 1.67 | 1.67 | 1.68 | 1.74 | 1.81 | 1.93 | 1.93 | 1.87 | 1.85 | 1.83 | 1.76 | 1.76 | 1.72 | 1.75 | 1.92 | 1.83 | 1.82 | 1.79 | 1.85 | 1.86 | 1.83 | 1.83 | 1.82 | 1.81 | 1.89 | 1.89 | 1.92 | 1.93 | 1.96 | 1.92 | 1.86 | 1.86 | 1.86 | 1.93 | 1.87 | 1.85 | 1.72 | 1.71 | 1.71 | 1.72 | 1.75 | 1.81 | 1.82 | 1.75 | 1.71 | 1.67 | 1.68 | 1.65 | 1.65 | 1.65 | 1.67 | 1.69 | 1.75 | 1.64 | 1.57 | 1.44 | 1.6 | 1.69 | 1.68 | 1.72 | 1.69 | 1.71 | 1.67 | 1.64 | 1.49 | 1.46 |
0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.03 | 0.03 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.03 | 0.03 | 0.03 | 0.03 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.04 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.01 | 0.01 | 0.01 | 0.01 | 0.03 | 0.03 | 0.03 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.01 | 0.01 | 0.01 | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.04 |
0.15 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.15 | 0.14 | 0.17 | 0.18 | 0.18 | 0.18 | 0.18 | 0.18 | 0.19 | 0.19 | 0.19 | 0.19 | 0.21 | 0.21 | 0.21 | 0.19 | 0.21 | 0.22 | 0.22 | 0.24 | 0.24 | 0.24 | 0.24 | 0.24 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.25 | 0.25 | 0.25 | 0.26 | 0.26 | 0.28 | 0.28 | 0.29 | 0.25 | 0.25 | 0.24 | 0.22 | 0.22 | 0.21 | 0.21 | 0.21 | 0.21 | 0.21 | 0.19 | 0.21 | 0.21 | 0.21 | 0.01 | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | nan | 0.01 | 0.01 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 | 0.04 | 0.04 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.04 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 | 0.01 |
0.31 | 0.25 | 0.21 | 0.19 | 0.19 | 0.19 | 0.19 | 0.18 | 0.19 | 0.21 | 0.21 | 0.21 | 0.21 | 0.22 | 0.26 | 0.26 | 0.26 | 0.26 | 0.29 | 0.28 | 0.26 | 0.26 | 0.26 | 0.26 | 0.28 | 0.26 | 0.24 | 0.24 | 0.22 | 0.24 | 0.25 | 0.25 | 0.25 | 0.26 | 0.29 | 0.28 | 0.28 | 0.28 | 0.29 | 0.29 | 0.29 | 0.29 | 0.29 | 0.29 | 0.25 | 0.25 | 0.25 | 0.25 | 0.26 | 0.26 | 0.26 | 0.26 | 0.26 | 0.26 | 0.26 | 0.26 | 0.28 | 0.28 | 0.26 | 0.26 | 0.26 | 0.26 | 0.25 | 0.24 | 0.19 | 0.19 | 0.19 | 0.19 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.15 | 0.14 | 0.15 | 0.15 | 0.15 | 0.18 | 0.17 | 0.15 | 0.15 | 0.15 | 0.12 | 0.11 | 0.12 | 0.14 | 0.14 | 0.14 | 0.15 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.18 | 0.18 | 0.18 | 0.17 | 0.17 | 0.17 | 0.17 | 0.18 | 0.18 | 0.18 | 0.18 | 0.17 | 0.17 | 0.18 | 0.17 | 0.18 | 0.18 | 0.18 | 0.18 | 0.19 | 0.19 | 0.21 | 0.21 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 | 0.21 | 0.21 | 0.22 | 0.21 | 0.21 | 0.21 | 0.21 | 0.21 | 0.21 | 0.21 | 0.19 | 0.18 | 0.18 | 0.17 | 0.15 | 0.15 | 0.15 | 0.15 | 0.15 | 0.15 | 0.14 | 0.14 | 0.14 | 0.14 | 0.14 | 0.17 | 0.18 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.17 | 0.15 | 0.15 | 0.14 | 0.14 | 0.14 | 0.14 | 0.12 | 0.12 | 0.11 | 0.11 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.12 | 0.12 | 0.12 | 0.12 | 0.11 | 0.11 | 0.12 | 0.12 | 0.12 | 0.12 | 0.12 | 0.12 | 0.12 | 0.12 | 0.12 | 0.14 | 0.12 | 0.14 | 0.15 | 0.15 | 0.15 | 0.15 | 0.17 | 0.17 | 0.17 | 0.17 |
You can also run the extraction directly to a file, a thing that can get handy when you have to run a very big bed file. You just need to specify a target file.
from pybwtool import extract extract( bed_path="path/to/my/bed_file.bed", bigwig_path="path/to/my/bigwig_file.bigwig", target="target.bed" )
Common fixes for getting bwtool to work
Consider looking at the Travis-CI configuration. If it works there, it should also work for you.
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