Skip to main content

Python reimplementation of mProphet peak scoring

Project description

pyprophet
=========

python reimplementation of mProphet algorithm. For more information, see the following publication:

Reiter L, Rinner O, Picotti P, Hüttenhain R, Beck M, Brusniak MY, Hengartner MO, Aebersold R.
*mProphet: automated data processing and statistical validation for large-scale
SRM experiments.* **Nat Methods.** 2011 May;8(5):430-5. [doi:
10.1038/nmeth.1584.](http://dx.doi.org/10.1038/nmeth.1584) Epub 2011 Mar 20.

In short, the algorithm can take targeted proteomics data, learn a linear
separation between true signal and the noise signal and then compute a q-value
(false discovery rate) to achieve experiment-wide cutoffs.


Installation
============

Install *pyprophet* from Python package index:

```
$ pip install numpy
$ pip install pyprophet
```

or:

```
$ easy_install numpy
$ easy_install pyprophet
```


Running pyprophet
=================

*pyoprophet* is not only a Python package, but also a command line tool:

```
$ pyprophet --help
```

or:

```
$ pyprophet --delim=tab tests/test_data.txt
```


Running tests
=============

The *pyprophet* tests are best executed using `py.test`, to run the tests use:

```
$ pip install pytest
$ py.test tests
```

Project details


Release history Release notifications | RSS feed

Download files

Download the file for your platform. If you're not sure which to choose, learn more about installing packages.

Source Distribution

pyprophet-0.13.0.tar.gz (118.3 kB view details)

Uploaded Source

File details

Details for the file pyprophet-0.13.0.tar.gz.

File metadata

  • Download URL: pyprophet-0.13.0.tar.gz
  • Upload date:
  • Size: 118.3 kB
  • Tags: Source
  • Uploaded using Trusted Publishing? No

File hashes

Hashes for pyprophet-0.13.0.tar.gz
Algorithm Hash digest
SHA256 d4d1245282ec99898eb6092e898845ef87c7f6b3a6e67dd7152ca72df2c09b11
MD5 44dad601b07271a1f1af2cb13aa8143d
BLAKE2b-256 48042960419cef8de9680b7314be765c3c431e9000863d38a5b31824cdd5f566

See more details on using hashes here.

Supported by

AWS Cloud computing and Security Sponsor Datadog Monitoring Depot Continuous Integration Fastly CDN Google Download Analytics Pingdom Monitoring Sentry Error logging StatusPage Status page