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Hierarchical deconvolution of bulk transcriptomics

Project description

Rectangle

Tests Documentation

Rectangle embodies a ”second-generation” deconvolution methodology, setting itself apart from other second-generation methods through its efficiency in signature creation and its handling of challenges within the deconvolution process. To establish a precise deconvolution method, we employ a hierarchical analysis approach, incorporate mRNA bias correction, and provide an estimation of unknown cellular content.

Getting started

Please refer to the documentation. In particular, the

Installation

You need to have Python 3.10 or newer installed on your system. If you don't have Python installed, we recommend installing Mambaforge.

How to install Rectangle:

Install the latest release of Rectangle from PyPI <https://pypi.org/project/rectanglepy/>:

pip install rectanglepy

Release notes

See the changelog.

Contact

If you found a bug, please use the issue tracker.

Citation

t.b.a

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