revolutionhtl 1.0.2

REvolutionH-tl: Reconstruction of Evolutionary Histories tool

Bioinformatics tool for the reconstruction of evolutionary histories. Input: fasta files or sequence alignment hits, Output: event-labeled gene trees and reconciliations.

Bioinformatics & complex networks lab

• José Antonio Ramírez-Rafael [[e-mail]]
• Maribel Hernandez-Rosales [[e-mail] ]

Install

pip install revolutionhtl

Requirements

Python >=3.7

If you want to run sequence alignments using revolutionhtl, then install Diamond.

Usage

Go to the wiki for details and an example.

python -m revolutionhtl <arguments>

Pipeline

1. Orthogroup & best hit selection. Input: alignment hits (generate this using revolutionhtl.diamond) .
2. Orthology and gene tree reconstruction. Input: best hits (generate this at step 1).
3. Species tree reconstruction. Input: gene trees (generate this at step 2).
4. Tree reconciliation. Input: gene and species trees (generate this at steps 2 and 3).

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