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Light-weight Python Computational Pipeline Management

Project description


The Ruffus module is a lightweight way to add support for running computational pipelines.

Computational pipelines are often conceptually quite simple, especially if we breakdown the process into simple stages, or separate tasks.

Each stage or task in a computational pipeline is represented by a python function Each python function can be called in parallel to run multiple jobs.

Ruffus was originally designed for use in bioinformatics to analyse multiple genome data sets.


Ruffus documentation can be found here , with download notes , a tutorial and an in-depth manual .


The purpose of a pipeline is to determine automatically which parts of a multi-stage process needs to be run and in what order in order to reach an objective (“targets”)

Computational pipelines, especially for analysing large scientific datasets are in widespread use. However, even a conceptually simple series of steps can be difficult to set up and maintain.


The ruffus module has the following design goals:

  • Lightweight

  • Scalable / Flexible / Powerful

  • Standard Python

  • Unintrusive

  • As simple as possible


Automatic support for

  • Managing dependencies

  • Parallel jobs, including dispatching work to computational clusters

  • Re-starting from arbitrary points, especially after errors (checkpointing)

  • Display of the pipeline as a flowchart

  • Managing complex pipeline topologies

A Simple example

Use the @follows(…) python decorator before the function definitions:

from ruffus import *
import sys

def first_task():
    print "First task"

def second_task():
    print "Second task"

def final_task():
    print "Final task"

the @follows decorator indicate that the first_task function precedes second_task in the pipeline.

The canonical Ruffus decorator is @transform which transforms data flowing down a computational pipeline from one stage to teh next.


Each stage or task in a computational pipeline is represented by a python function Each python function can be called in parallel to run multiple jobs.

  1. Import module:

    import ruffus
  1. Annotate functions with python decorators

  2. Print dependency graph if you necessary

    • For a graphical flowchart in jpg, svg, dot, png, ps, gif formats:

      pipeline_printout_graph ("flowchart.svg")

    This requires dot to be installed

    • For a text printout of all jobs

  3. Run the pipeline:


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