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Manifold preserving marker selection for single-cell data

Project description

SCMER - Manifold Preserving Feature Selection

Documentation Status PyPI PyPI - Downloads Code Ocean

SCMER is a feature selection methods designed for single-cell data analysis. It selects a compact sets of markers that preserve the manifold in the original data. It can also be used for data integration by using features in one modality to match the manifold of another modality.

Tutorials

Tutorials are available at https://scmer.readthedocs.io/en/latest/examples.html

You may start with the Melanoma data (Tiorsh et al.).

Full Documentation

Detailed documentation is available at https://scmer.readthedocs.io/en/latest/

The mechanism and capabilities of SCMER is detailed in our pre-print Single-Cell Manifold Preserving Feature Selection (SCMER)

Publication

Single-cell manifold-preserving feature selection for detecting rare cell populations Nature Computational Science (2021)

Contact

I do monitor the "Issues" and aim to clear any issues in a few weeks. If you have an urgent request, please email liang.shaoheng@rice.edu.

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