scPCA - A probabilistic factor model for single-cell data
scPCA is a versatile matrix factorisation framework designed to analyze single-cell data across diverse experimental designs.
scPCA is a young project and breaking changes are to be expected.
scPCA in a nutshell
scPCA enables the analysis of single-cell RNA-seq data across condtions. In simple words, it enables the incorporation of a design (model) matrix that encodes the experimental design of the dataset and infers how the gene loading weight vectors change from a specified reference condition to the treated condtion.
