RNA Structure Ensemble Inference via Sequencing, Mutation Identification, and Clustering
Project description
SEISMIC-RNA
RNA Structure Ensemble Inference via Sequencing, Mutation Identification, and Clustering
About
SEISMIC-RNA analyzes deep sequencing datasets from RNA mutational profiling experiments, such as DMS-MaPseq and SHAPE-MaP. This software introduces an optimized implementation of the original algorithm DREEM for quantifying and clustering mutations to infer RNA structural ensembles.
Contributors
SEISMIC RNA has been developed in Silvi Rouskin's lab at Harvard Medical School by the following individuals:
Installation
Instructions for installing SEISMIC-RNA are in INSTALL.md.
Usage
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Development
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Issues
The issue page of the GitHub repository is the official location for reporting bugs and other issues. Before opening a new issue, please check if a similar issue already exists.
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