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gene signature score for gene expression matrix

Project description

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sigc

install

pip install sigc

core usage

import sigc

kegg_metabolism = sigc.metabolism_sigs(resources='KEGG')
# other custom signature gene sets also support

df = pd.read_table("cells_X_genes.mat", header=0, index_col=0)

sig_mtx = sigc.sigc_score(df, kegg_metabolism, method="AUCell")
# sig_mtx: cells_X_signatures

signature example

name

description

member

Glycolysis

00010

HK3

Glycolysis

00010

HK1

Glycolysis2

describ2

geneX

Documentation

Extensive documentation and tutorials are available at https://sigc.readthedocs.io

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