six-frame genome-inferred libraries for LC-MS/MS
Six-frame Genome-Inferred Libraries for LC-MS/MS
What is Sixgill?
Sixgill is a tool for using shotgun metagenomics sequencing reads to construct databases of ‘metapeptides’: short protein fragments for database search of LC-MS/MS metaproteomics data. A comprehensive set of resources for building and using metapeptide databases is here.
Required Python versions
Sixgill supports Python 2.7
Get pip, if you don’t have it yet.
Install Sixgill and its dependencies:
pip install biopython pysam sixgill
The Sixgill wiki contains more detailed information on using Sixgill.