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Generate mutated sequence files from a reference genome.

Project description

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Generate mutated sequence files from a reference genome.

SNP Mutator was developed by the United States Food and Drug Administration, Center for Food Safety and Applied Nutrition.

Features

  • Reads a fasta file and generates any number of mutated fasta replicate files.

  • Mutations can be any number of single-base substitutions, insertions, and deletions at randomly chosen positions, uniformly distributed across the genome.

  • Generates a summary file listing the original base and the mutation for all mutated positions.

Citing SNP Mutator

To cite SNP Mutator, please reference the SNP Mutator GitHub repository:

https://github.com/CFSAN-Biostatistics/snp-mutator

License

See the LICENSE file included in the SNP Mutator distribution.

History

0.1.1 (2015-06-17)

  • Remove spaces from the summary file column headings. This will simplify downstream analysis in some scripting languages.

0.1.0 (2015-05-21)

  • First release on GitHub, Read the Docs, and PyPI.

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