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SSFP simulation

Project description

SSFP

Simple steady-state free precession simulation. The goal is to provide a simple to use, pip-installable solution for simulating this wonderful pulse sequence.

In this package:

  • bSSFP: bssfp()
  • GS solution: gs_recon()

Installation

Should be as easy as:

pip install ssfp

Usage

See ssfp.examples for typical usage. You can run examples like:

python -m ssfp.examples.basic_bssfp

Balanced steady-state free precession can be called through bssfp(). This is an implementation of equations [1–2] in [1]. These equations are based on the Ernst-Anderson derivation [2] where off-resonance is assumed to be subtracted as opposed to added (as in the Freeman-Hill derivation [3]). Hoff actually gets Mx and My flipped in the paper, so we fix that here. We also assume that the field map will be provided given the Freeman-Hill convention.

from ssfp import bssfp

# Here's the simplest usage, see docstring for all the possible
# function arguments
sig = bssfp(T1, T2, TR, alpha)

We can also easily get the Geometric Solution to the elliptical signal model as described in [1] as follows:

from ssfp import gs_recon
recon = gs_recon(phased_cycled_images, pc_axis=-1)

# Notice that we can specify the axis where the phase-cycles live

PLANET [4] is a method for simultaneous T1, T2 fitting for bSSFP phase-cycled data. Call like this:

from ssfp import planet

# For a single pixel:
Meff, T1, T2 = planet(
    phased_cycled_pixels, alpha, TR, T1_guess,
    pcs=np.deg2rad([0, 90, 180, 270, etc...]))

References

[1](1, 2) Xiang, Qing‐San, and Michael N. Hoff. “Banding artifact removal for bSSFP imaging with an elliptical signal model.” Magnetic resonance in medicine 71.3 (2014): 927-933.
[2]Ernst, Richard R., and Weston A. Anderson. “Application of Fourier transform spectroscopy to magnetic resonance.” Review of Scientific Instruments 37.1 (1966): 93-102.
[3]Freeman R, Hill H. Phase and intensity anomalies in fourier transform NMR. J Magn Reson 1971;4:366–383.
[4]Shcherbakova, Yulia, et al. “PLANET: an ellipse fitting approach for simultaneous T1 and T2 mapping using phase‐cycled balanced steady‐state free precession.” Magnetic resonance in medicine 79.2 (2018): 711-722.

Project details


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