Linear mixed model to study multivariate genotype-environment interactions
Project description
# Struct-lmm
[![Travis](https://img.shields.io/travis/com/limix/struct-lmm.svg?style=flat-square&label=linux%20%2F%20macos%20build)](https://travis-ci.com/limix/struct-lmm) [![Documentation](https://img.shields.io/readthedocs/struct-lmm.svg?style=flat-square&version=stable)](https://struct-lmm.readthedocs.io/)
Structured Linear Mixed Model (StructLMM) is a computationally efficient method to test for and characterize loci that interact with multiple environments [1].
This a standalone module that implements the basic functionalities of StructLMM. However, we recommend using StructLMM using [LIMIX2](https://limix.readthedocs.io/en/2.0.0/index.html) as this additionally implements:
multiple methods for GWAS;
methods to characterize GxE at specific variants;
command line interface.
[1] Moore R, Casale FP, Bonder MJ, Horta D, Franke L, Barroso I, Stegle O, BIOS Consortium. A linear mixed model approach to study multivariate gene-environment interactions. bioRxiv. 2018 Jan 1:270611.
## Install
From terminal, it can be installed using [pip](https://pypi.python.org/pypi/pip):
`bash pip install struct-lmm `
## Documentation
The public interface and a quick start in python are available at [http://struct-lmm.readthedocs.io/](http://struct-lmm.readthedocs.io/).
## Problems
If you encounter any problem, please, consider submitting a [new issue](https://github.com/limix/struct-lmm/issues/new).
## Authors
Francesco Paolo Casale - [https://github.com/fpcasale](https://github.com/fpcasale)
Danilo Horta - [https://github.com/horta](https://github.com/horta)
Rachel Moore - [https://github.com/rm18](https://github.com/rm18)
Oliver Stegle - [https://github.com/ostegle](https://github.com/ostegle)
## License
This project is licensed under the Apache License (Version 2.0, January 2004) - see the [LICENSE](LICENSE) file for details
Project details
Release history Release notifications | RSS feed
Download files
Download the file for your platform. If you're not sure which to choose, learn more about installing packages.