Symetrics API
Project description
A package to access SYMETRICS database. SYMETRICS database is a consolidation of metrics for synonymous variants which were derived from a number of computational tools each of which contributing to attribute specific metrics such as SYNVEP for general functional constraints, SpliceAI for splicing effect, SILVA for obtaining GERP++ (phylogenetic related constraints) CpG/CpG_Exon, dRSCU/RSCU for codon usage and SURF for rna stability. The package also includes a result of the analysis of the influence of each variants exceeding set threshold per metrics defined constituting to a score assigned to a gene
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