trisicell 0.0.5

Trisicell - Scalable tumor phylogeny reconstruction and validation from single-cell data

Trisicell - Scalable tumor phylogeny reconstruction and validation from single-cell data

Trisicell (Triple-toolkit for single-cell tumor phylogenetics), pronounced as “tricycle”, is a new computational toolkit for scalable tumor phylogeny reconstruction and evaluation from scRNAseq (as well as single-cell genome or exome sequencing) data. Trisicell utilizes expressed SNVs and Indels to infer evolutionary relationships between genomic alterations and the cells that harbor them.

Manuscript

Please see our preprint on bioRxiv to learn more.

Support

Feel free to submit an issue or send us an email. Your help to improve Trisicell is highly appreciated.

Trisicell was developed in collaboration between the Cancer Data Science Laboratory (CDSL) and the Laboratory of Cancer Biology and Genetics (LCBG) at the National Cancer Institute (NCI).