Toolkit for benchmarking, merging, and annotating Structural Variants
📚 WIKI page has detailed user documentation.
🛠️ Developer Docs for the truvari API.
📈 See Updates on new versions.
📝 Read our Papers (#1, #2) to learn more.
💻 Installation
Truvari uses Python 3.6+ and can be installed with pip:
python3 -m pip install Truvari
For details and more installation options, see Installation on the wiki.
⏩ Quick Start
Each sub-command contains help documentation. Start with truvari -h to see available commands.
The current most common Truvari use case is for structural variation benchmarking:
truvari bench -b base.vcf.gz -c comp.vcf.gz -f reference.fa -o output_dir/
Find more matches by harmonizing phased variants using refine:
truvari refine output_dir/
Use Truvari's comparison engine to consolidate redundant variants in a merged multi-sample VCF:
bcftools merge -m none sampleA.vcf.gz sampleB.vcf.gz | bgzip > merge.vcf.gz
tabix merge.vcf.gz
truvari collapse -i merge.vcf.gz -o truvari_merge.vcf
🧬 Truvari Commands
- bench - Performance metrics from comparison of two VCFs
- collapse - Collapse possibly redundant VCF entries
- refine - Automated bench result refinement with phab
- anno - Add SV annotations to a VCF
- phab - Harmonize variant representations using MSA
- consistency - Consistency report between multiple VCFs
- vcf2df - Turn a VCF into a pandas DataFrame
- segment - Normalization of SVs into disjointed genomic regions
- stratify - Count variants per-region in vcf
- divide - Divide a VCF into independent shards
- ga4gh - Consolidate benchmarking result VCFs
🔎 More Information
All documentation about Truvari is on the WIKI. Additional information about using Truvari can be found in Discussions
1 maintainer
Metadata
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Release files for truvari 5.3.0
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Source distribution (sdist)
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| truvari-5.3.0.tar.gz | 92.4 kB | Details |
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|---|---|---|---|---|
| truvari-5.3.0-py3-none-any.whl | Python 3 | none | any | Details |
Total release size: 204.5 kB
Release files / truvari-5.3.0.tar.gz
| Download URL | truvari-5.3.0.tar.gz |
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| Tags | Python 3 |
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