4 projects
sonnia
SoNNia is a Python 3 software developed to infer selection pressures on features of amino acid CDR3 sequences. SoNNia takes as input TCR CDR3 amino acid sequences with V and J genes. Its output is sequence-level selection factors which indicate how more or less represented this sequence would be in the selected pool as compared to the pre-selected pool. These in turn could be used to calculate the probability of observing any sequence after selection and sample from the selected repertoire.
sonia
SONIA is a python 3.6 software developed to infer selection pressures on features of amino acid CDR3 sequences. The model can be used to calculate the probability of observing any sequence after selection and sample from the selected repertoire.
olga
Compute generation probability of CDR3 sequences
igorpy
Python package to manipulate and run IGoR data files