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Tool kit for single-cell methylome data analysis.

Project description

ALLCools

  • A toolkit for ALLC format and bulk/single-cell methylation sequencing analysis.
  • It provides all necessary functions about generating, manipulating and transfering 2 file formats:
    • the ALLC format, a tab-sparated text format storing base-level raw methylation information for 1 sample.
    • the MCDS format, a integrated HDF5 dataset storing region-level raw methylation information for a group of samples/cells.
  • This package is still under active development

ALLCools Function Map

Get Start

requirements

ALLCools requires python > 3.6

installation

git clone https://github.com/lhqing/ALLCools.git
cd ALLCools
pip install .

update

# cd /path/to/ALLCools
git pull
pip install .

use the ALLCools

  • CLI (recommand for non-python users)
allcools -h
allcools [FUNCTION_NAME] -h
  • API (recommand for integrating ALLCools with other python package, such as pybedtools, pybigwig, deeptools.)
from ALLCools.api import *

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