single cell RNA profiling analysis of imaging-based spatial transcriptomics data
Project description
ComSeg framework
A detail documentation is available Here https://comseg.readthedocs.io/en/latest/userguide.html
Single cell spatial RNA profiling
ComSeg is an algorithm for single cell spatial RNA profiling in image-based transcriptomic data.
It takes as input a csv with the spot coordinates and output an anndata object with the enes expression and coordinates of each cell.
Installation
First, create a dedicated conda environment using Python 3.8
conda create -n ComSeg python=3.8
conda activate ComSeg
To install the latest github version of this library run the following using pip
pip install git++https://github.com/tdefa/ComSeg
or alternatively you can clone the github repository
git clone +https://github.com/tdefa/ComSeg
cd cnn_framework
pip install -e .
A tutorial notebook can be found here : https://comseg.readthedocs.io/en/latest/userguide.html
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