Dynast: Inclusive and efficient quantification of labeling and splicing RNAs for time-resolved metabolic labeling based scRNA-seq experiments
Getting started - Pipeline usage - Technical information - Full documentation
Dynast is a command-line pipeline that preprocesses data from metabolic labeling scRNA-seq experiments and quantifies the following four mRNA species: unlabeled unspliced, unlabeled spliced, labeled unspliced and labeled spliced. In addition, dynast can perform statistical estimation of these species through expectation maximization (EM) and Bayesian inference.
Key features
- Complete quantification of labeling and splicing of RNA.
- Unlabeled unspliced, unlabeled spliced, labeled unspliced, labeled spliced species quantification.
- Highly paralellized and optimized pipeline procedures.
- Statistical estimation procedure that corrects the observed unlabeled and labeled counts via a Bayesian inference framework.
1 maintainer
Metadata
1 maintainer
Release files for dynast-release 1.0.1
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| File | Size | Uploaded | Provenance | Actions |
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| dynast-release-1.0.1.tar.gz | 4.3 MB | Without provenance | Details for dynast-release-1.0.1.tar.gz |
Release files / dynast-release-1.0.1.tar.gz
| Download URL | dynast-release-1.0.1.tar.gz |
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| Size | 4.3 MB |
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twine/4.0.1 CPython/3.8.13
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Security for dynast-release 1.0.1
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